USC Football vs. California Prediction and Odds for Week 10 CFB (Trojans to dominate)

USC Football is set to play their longtime rival in the Cal Golden Bears on Saturday. Sure, it's not much of a rivalry on the field, as USC leads the series 71-31-5, but it is a rivalry just in the sense that the two squads play every year. That tradition may not continue in the Big Ten, but it will this year and next, while SC is still in the PAC-12.

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USC is 7-1 and the No. 9-ranked team in the AP Poll, while Cal is a tough 3-5. SC learned last week, though, that they can't sleepwalk through any opponent. Any game in-conference can't be seen as a cupcake; even if the Trojans are favored BIG.

USC Football vs. Cal Odds Week 10

The spread for the game is -21.5 USC Football. It's -105 to take that, and -115 to take the +21.5 California. These odds are according to WynnBET. USC has been favored in every single game they've played this year except for the Utah game. That continues this week with the Trojans expected to blow out the Bears.

USC Football vs. Cal Prediction Week 10

Feel free to take USC Football covering that spread. Cal is supposed to be a defensive-minded team considering that they have a defensive-minded head coach in Justin Wilcox. Still, however, they are awful on defense; allowing 25 points per game (63rd in FBS). They meet a terrible matchup with the high-powered Trojan offense that's racking up 41(!) points per game. That's tied for eighth in the FBS.

When Cal's bad defense is their strong side of the ball, it's quite the problem. Their offense is even way worse, as they are putting up just 23.4 points per game. That's outside the top 100 in the country. This has the makings of a get-right game for SC's defense. Again, pick USC to win this game, and pick them to win by that 22 or more-point margin.

Game odds refresh periodically and are subject to change