Full guide to Iowa vs USC: How to watch, weather, odds, history and more

USC celebrates homecoming this week with a high-stakes conference matchup against Iowa. The Trojans look to carry their momentum and extend their two-game winning streak, while the Hawkeyes travel to Los Angeles for a top-25 showdown after a narrow home loss to Oregon last weekend.

When and Where is Iowa vs USC

Matchup: No. 17 USC (7-2, 5-1 B1G) vs No. 21 Iowa (6-4, 4-2 B1G)

Date: Saturday, Nov. 15, 2025

Kick: 12:30 p.m. PT (3:30 p.m. ET)

Where: United Airlines Field at L.A. Memorial Coliseum, Los Angeles Coliseum

TV: Big Ten Network

Streaming: FuboTV 

Radio: ESPN LA 710

Rankings for USC and Iowa

USC enters the weekend ranked No. 17 in the College Football Playoff (CFP) rankings, moving up two spots from last week. Meanwhile, the Iowa Hawkeyes fell one position from No. 20 to No. 21 after their narrow home defeat to Oregon.

Betting Odds for USC vs. Iowa

USC enters the matchup as a 7.0-point favorite and is listed at -250 on the moneyline, with the over/under set at 49.5. Fans should check their preferred sportsbook for the latest odds and updates.

Weather Forecast for USC vs. Iowa

Game-time conditions in Los Angeles are expected to be inclement, with temperatures around 63°F, cloudy skies, winds near 10 mph, and a 75% chance of rain.

USC and Iowa Previous Results

• USC 38, Northwestern 17 (Nov. 7): Wide receiver Makai Lemon had a career performance, hauling in 11 catches for 161 yards and adding two touchdowns, as the Trojans dominated the Wildcats in the second half.

• Iowa 16, Oregon 18 (Nov. 8): Iowa grabbed a late lead in the fourth quarter, but Oregon responded with a game-winning field goal with just three seconds left, spoiling the Hawkeyes’ upset hopes.

USC vs. Iowa Series History

USC and Iowa have faced each other ten times, with the Trojans winning seven of those contests. Their most recent meeting came in the 2019 Holiday Bowl, where Iowa emerged victorious, 49-24.

Key Storylines and Matchup Notes for USC and Iowa

• The Trojans will benefit from an extra day of preparation after playing last Friday against Northwestern. They’ll also be playing their second consecutive home game, a stretch they haven’t had since the first two weeks of the season.

• USC remains undefeated at home with a perfect 5-0 record. The Trojans will aim to extend that streak to six as they celebrate homecoming this week.

• After his career performance last week, Makai Lemon enters the Iowa game as the Big Ten’s leading receiver, topping the conference with 937 yards and averaging 15.4 yards per catch.

• The Trojans have limited their opponents to 20 points or fewer in five games this season, while Iowa has failed to reach 20 points in three games so far.