1) The Turnover Battle
Under Brian Kelly, the Irish are 12-0 when they do not commit a turnover. Unfortunately for Notre Dame, Tommy Rees has thrown four interceptions in the last two games after throwing just two in the first four games. In his last full season as the starter for the Irish, Rees threw 14 interceptions.
On the other side, USC forced seven turnovers in the first two games of the season, but have only taken the ball away once in the last four. In a road rivalry game, momentum is everything, especially with too evenly matched teams.